AKT1 and human papilloma virus infection: KEGG analysis of the differentially expressed genes (DEGs) between the low- and high-risk groups showed that they were mainly enriched in cancer-associated pathways, such as the PI3K-Akt signaling pathway [24], human papillomavirus infection [25], breast cancer, proteoglycans in cancer, protein digestion and absorption, and hepatitis C [26] (Figure 4C, 4D).