Subsequently, the most consistentnetwork-related gene expression in MSCs cultured on elastic hydrogelsinvolved glucose metabolism disorders and inflammatory responses (consistencyscore +2.83 and +1.789, respectively), thereby predicting the regulationof these functions by an activation of CRYAB, NR1H2, and PIM1 and by an inhibition of IRF1 and NR1/2. This evidence concerns the gene CRYAB and glucose metabolism disease.