Furthermore, quantification analysis of postsynaptic elements in CA2 showed that compared to NNCs, the amount of PSD95+ area was increased by twofold in the demyelinated MS hippocampus (P = 0.0031) while, in striking contrast, the amount of gephyrin+ area decreased in MS-DM hippocampi (P = 0.0022, Fig. 2). This evidence concerns the gene DLG4 and myeloid sarcoma.