Combining the control, myelinated and demyelinated MS hippocampi, we found a significant and positive correlation between the extent of C1q immunoreactivity and the extent of vGLUT1+ immunoreactivity (Spearman correlation coefficient, r = 0.66, P = 0.0001, n = 28) but not with the extent of PSD95 immunoreactivity (r = 0.28, P = 0.15, n = 28). Here, DLG4 is linked to myeloid sarcoma.