Inflammation playsa major role inthe pathology of Alzheimer’s disease.15 We have previously demonstrated no significant alteration in theconcentrations of interleukins (IL-1b, IL-5, IL-6, and IL12) in thebrains of APPswe mice after treatment with SST-scFv8D3.6 However, this is not a complete list of cytokines,and the immune system might respond to treatments in several waysthat do not include alterations in interleukin concentrations. Here, IL1B is linked to early-onset autosomal dominant Alzheimer disease.