Increased adiponectin level might be due to the treatment to COPD patients with β agonists (75), and we consider adiponectin to display anti-inflammatory attributes by inhibiting the expression of the pro-inflammatory cytokine TNFα and the transcription factor nuclear factor kappa beta (NF-κb) (76) and by mediating lung-protective properties (75). The gene discussed is TNF; the disease is chronic obstructive pulmonary disease.