Thus, the aim of this study was to characterize the ABA levels in the peripheral blood and the expression pattern of the ABA receptor LANCL2, as well as PPAR-γ on peripheral blood mononuclear cells of COPD patients and asthmatics, and to correlate these data with disease severity and other clinical parameters associated with COPD and COPD-associated comorbidities. This evidence concerns the gene PPARG and chronic obstructive pulmonary disease.