After adjusting for all factors (age, menopausal status, clinical tumor stage, clinical nodal stage, HR status, Ki-67, and taxane treatment) in the multivariable analysis, there were still no significant differences between four-cycle and six-cycle groups (OR = 1.252, 95% CI 0.904 - 1.733, p = 0.176, Table 2 and Figure 3). The gene discussed is MKI67; the disease is neoplasm.