SPP1, CRYAB, NNMT and HILPDA were highly expressed in tumour cells (ccRCC1); GSTA2, BHMT and ADSSL1 were highly expressed in tumour cells 1 (ccRCC2); and HIF1A-AS2, DNAH11 and EGOT were highly differentially expressed in tumour cells 2 (ccRCC2). The gene discussed is BHMT; the disease is neoplasm.