DUXAP9 and nonpapillary renal cell carcinoma: To identify the impact of upregulated DUXAP9 in localized ccRCC, we knocked down DUXAP9 using shRNAs targeting DUXAP9 in Umrc6 (17) and Caki-1 cells (Figures 3A, B) and overexpressed DUXAP9 in 786-O cells (Figure 3C).