Due to these transmembrane transport characteristics, Mitsuoka et al. synthesized two novel dipeptides [l-phenylalanyl sarcosine (Phe-Sar) and 4-(4-methoxyphenyl)-l-phenylalanyl sarcosine (Bip(OMe)-Sar)] and successfully inhibited the human pancreatic cancer cell line AsPC-1, demonstrating that PEPT1 has a promising role as an anti-pancreatic cancer progression target (Mitsuoka et al., 2010). This evidence concerns the gene SLC15A1 and pancreatic neoplasm.