The Plasmodium falciparum (Pf) circumsporozoite protein (CSP) is a leading target in ongoing malaria vaccine development efforts and the antigenic component of the MosquirixTM (RTS,S/AS01) vaccine, a recombinant virus-like protein platform containing large portions of the central repeat and C-terminal regions of PfCSP 3D7. Here, DNAJC5 is linked to malaria.