CD274 and non-small cell lung carcinoma: In a follow-up study published almost two years later, (Kargl et al., 2017) investigated associations of neutrophil colonization of the TME in patients with NSCLC with anti-tumor immunity according to intratumoral migration of CD8+ T cells, as well as with responsiveness to PD-1-/PD-L1 monoclonal antibody-based targeting.