Tumor tissues were also collected for detecting expression levels of β-catenin, Cav-1, as well as metastatic markers by Western blotting analysis, and it was found that CP administration led to a reduction in the expression levels of β-catenin, Cav-1 and Vimentin as well as an increase in E-cadherin level (Figure 8E). Here, VIM is linked to neoplasm.