While IL-8 is a known neutrophil recruiter from the circulating blood to the site of infection (Höffs et al., 2016), IL-6 is related to immune response to microorganisms and its expression is directly influenced by the secretion of other pro-inflammatory cytokines, especially IL-1 (Tanaka et al., 2014). The gene discussed is CXCL8; the disease is infection.