The number of VGAT+ terminals per unit area (linear density) was lower in the CA1 pyramidal layer (313 ± 18.08/mm vs. 239.16 ± 15.03/mm in MD vs. control rats, n = 6 animals/group, t-test, p < 0.0001) and CA3 pyramidal layer (275.7 ± 23.4/ mm vs. 325.5 ± 18.8/mm in MD vs. control rats, n = 6 animals/group, t-test, p = 0.0022) regions of the hippocampus in MD rats compared to controls, whereas in the dentate gyrus granule cell layer (320.6 ± 23/mm vs. 312.5 ± 21/mm in MD vs. control rats, n = 6 animals/group, t-test, p = 0.54) values were similar for MD and control rats (Figure 6B). The gene discussed is SLC32A1; the disease is Menkes disease.