AHSG is associated with alopecia-mental retardation syndrome 1 (Reza Sailani et al., 2017), patients of familial amyloid polyneuropathy (FAP) carrying TTR Met30 mutation (Tanaka et al., 1994), and fibrinogen gamma chain (FGG) appear to be protected after ischemic stroke (Cheung et al., 2008). Here, TTR is linked to ischemic stroke.