In asthma similarly to control group the biggest changes in IL-8 mRNA expression after UPM exposure was found in epithelial/moDCs co-cultures (6.4 fold change (3.4–11.5 fold change) and in triple co-cultures (3.5 fold change (1.8–5.7 fold change). The gene discussed is CXCL8; the disease is asthma.