SQSTM1 and infection: A more recent study on enterovirus D68 (EV-D68) found a similar cleavage based strategy to be common among picornaviruses by testing SQSTM1/p62 cleavage upon infection with EV-D68, poliovirus 1 (PV), rhinovirus 1A (RV1A) and CVB3 as a positive control [16].