As labour is believed to be an inflammatory process, AKIP1 may function as a molecular switch in myometrium, promoting NFκB activitation; It has been reported that in breast cancer tissue there are at least three different splice variants of AKIP1 [26], further more these have distinct cellular localization [27] and different affinity binding for PKAc [28] and such could have an impact of NFκB activation. The gene discussed is NFKB1; the disease is breast carcinoma.