DRV1, ALX, and DRV2 were all expressed on healthy and sepsis CD16bright PMN, with mean fluorescent intensity (MFI) significantly increased in patients with sepsis by ~3-fold for DRV1, 5-fold for ALX, and 4-fold for DRV2 compared with healthy subjects (Figure 1B). This evidence concerns the gene GPR18 and Sepsis.