Using mixed linear effect models, we showed that tumor GR were significantly slower in mice treated with combined MEKi and anti‐CD73 antibody (GR = 7.91) than vehicle (GR = 18.36, P < 0.0001), anti‐CD73 antibody alone (GR = 10.97, P < 0.02), and MEKi alone (GR = 12.40, P < 0.001), respectively. Here, NT5E is linked to neoplasm.