IL-6 is a pleiotropic cytokine that regulates cell proliferation and inhibits apoptosis and has been proven to overexpress in many types of tumors, such as colon, liver, breast, brain tumor and NPC; furthermore, IL-6 activates multiple pro-proliferation and anti-survival proteins to stimulate growth of tumor cells [19–21]. This evidence concerns the gene IL6 and nasopharyngeal carcinoma.