None ofthe CBL/CBLB sites have roles described in PSP, but these proteinsare known regulators of receptors in trafficking via clathrin.47,48 Moreover, EGFR_Y1110 and EGFR_Y1197are both annotated to receptor internalization in PSP and inducingcell motility. The gene discussed is CBL; the disease is supranuclear palsy, progressive, 1.