FMO5 and breast carcinoma: The results showed that genes in the antioxidant pathways and cell proliferation pathways, such as cysteine and methionine metabolism, terpenoid backbone biosynthesis, iron uptake and transport, cell cycle, DNA replication and mismatch repair were upregulated in the high-risk breast cancer patients (Figure 7A), while oxidative damage-related pathways were significantly down-regulated, such as GTPases activate NADPH oxidases and oxidative damage (Figure 7B).