And there was a co-expression relationship between AC108474.1 and 5 ferroptosis-related genes (TAZ, ISCU, CAV1, PLIN4, and HIC1), including 1 ferroptosis driver, 2 ferroptosis suppressor and 2 ferroptosis marker, and AC108474.1 was a protective factor for breast cancer patients too. This evidence concerns the gene HIC1 and breast cancer.