More and more evidences indicate abnormal expression of p62 in various cancers, including liver (Inami et al., 2011), lung (Inoue et al., 2012), breast (Rolland et al., 2007), kidney (Li et al., 2013), colorectal (Ren et al., 2014), ovarian (Yan et al., 2019), and prostate cancers (Kitamura et al., 2006). Here, SQSTM1 is linked to cancer.