High CCL2 expression positively correlates with increased infiltration of tumor associated macrophages and predicts worse prognosis in multiple human and murine cancers (Fridlender et al., 2011; Qian et al., 2011; Tsuyada et al., 2012; Wolf et al., 2012; Bonapace et al., 2014; Li et al., 2017). This evidence concerns the gene CCL2 and cancer.