According to the result (Table 6), all the hub genes could effectively predict the OS of ACC patients (ASPM: AUC = 0.840, C-index = 0.827; AURKA: AUC = 0.786, C-index = 0.794; CCNB2: AUC = 0.830, C-index = 0.821; CDC20: AUC = 0.833, C-index = 0.838; KIF2C: AUC = 0.819, C-index = 0.823; NUF2: AUC = 0.811, C-index = 0.843). This evidence concerns the gene CDC20 and adrenal cortex carcinoma.