15,16 The benefit of SA binding is underscored by the clinical effectiveness of aldoxorubicin (INNO206; human serum albumin (HSA)-coupled doxorubicin derivative) and Abraxane® (HSA based nanoparticle encapsulation of paclitaxel) for the treatment of sarcoma,17 breast cancer,18 lung cancer,19 and pancreatic cancer.20 Several other HSA-anticancer drug conjugates are currently in clinical trials. This evidence concerns the gene ALB and sarcoma.