IRF3 and Rotavirus infection: Moreover, we have previously demonstrated that B. infantis MCC12, B. breve MCC1274 (32), L. rhamnosus CRL1505, Lactiplantibacillus plantarum CRL1506 (30), and L. plantarum MPL16 (38) significantly diminished A20 expression in PIE cells in the context of poly(I:C) stimulation or rotavirus infection, which was in line with the capacity of these strains to improve IRF3 activation and IFN-β production.