1. ATB patients exhibited higher expression of BTLA in mDCs and pDCs subsets than healthy controls.2. TB-driven BTLA expression in DCs impairs the expression of functional DC surrogate markers and suppress the ability of DCs to induce anti-TB Th17 and Th22 response while promoting Th2 and Foxp3+ Tregs. The gene discussed is FOXP3; the disease is tuberculosis.