Based on experimental animal studies, the inhibition of chemoattractants such as CXCL2 and CXCL8 might lead to the resolution of inappropriate neutrophil mobilization and NETs induction, leading to the improvement of vasculitis and atherosclerosis (Summers et al., 2010; Kanzaki et al., 2016; An et al., 2019). The gene discussed is CXCL8; the disease is atherosclerosis.