The relevance of TSPYL5 expression to radiation resistance of CSC-like NSCLC cells has been examined with NSCLC cells (A549 human lung adenocarcinoma cell line; H460 human large-cell lung carcinoma cell line) treated with fractionated γ-radiation33 [2 (or 1) Gy × 3 with a 3-day interval, a total of 6 (or 3) Gy]. The gene discussed is TSPYL5; the disease is lung large cell carcinoma.