The group of Lin have shown that the panel of four cytokines—IL-7, IL1R4/ST2, sgp130 and MCP-1 substantially correlated with GBM patient's overall survival27, as well as Elstner and his group proposed the protein profile formed of TSP1, HSP70, and IGFBP3, which was associated with more than 15 months survival after GBM tumour resection25. Here, IGFBP3 is linked to neoplasm.