Interestingly, after 20 days of co-culture, we detected a significant increase of tumor-promoting cytokines such as interleukin 6 (IL-6)62 and IL-863 (p = 7.5 × 10−7 and p = 0.0028, respectively), or positive regulators of immunosuppression such as chemokine ligand 264 (CCL2, p = 0.035) when compared to cultures containing tumor cells or HSPCs alone (Fig. 5j). The gene discussed is CCL2; the disease is neoplasm.