This expansion was not an upper limit however, as the lymphoid organs of naive mice immunized intravenously with SPAS-1 (H8) peptide in a TriVax formulation containing anti-CD40 and Poly I:C57 accumulated over 40-fold more SPAS-1 specific T cells than were generated by the tumor response (Fig. 1e). Here, CD40 is linked to neoplasm.