CD8A and Huntington disease: Single i.m. immunizations with MVA-SARS-2-S already induced S269–278-epitope–specific activated CD8+ T cells with mean numbers of 341 IFN-γ spot-forming cells (SFCs) in 106 splenocytes for LD and 275 SFCs for HD compared to control mice immunized with nonrecombinant MVA (no SFCs detectable) (Fig. 4A).