AKT3 and osteosarcoma: In Osteosarcoma, hsa_circ_001569 overexpression contributed to cisplatin resistance through the Wnt/β-catenin pathway, and similarly, in CRC, hsa_circ_0007031 and hsa_circ_0000504 overexpression promoted 5-FU resistance through the circRNA/miR-885-3p/AKT3 axis [104].