In group 2A, significant correlations were observed between fibrosis severity and ALP (R = 0.4; P = 0.03) and GGT levels (R = 0.5; P = 0.01); between cholestasis severity and duration of cholestasis (R = 0.8; P < 0.001), bilirubin levels (R = 0.6; P = 0.004), INR (R = 0.3; P = 0.04) and ALB (R = -0.3; P < 0.001); and between ductular proliferation severity and duration of cholestasis (R = 0.7; P < 0.001), INR (R = 0.7; P = 0.03) and ALB (R= -0.7; P < 0.001). The gene discussed is ALB; the disease is cholestasis.