It was found that JQ1, a BRD4 inhibitor, inhibited TSA‐induced ESCC cell migration (Figure 5B), and at least partially reversed TSA‐induced effects on the levels of p‐ERK1/2, PAI‐1, and all EMT markers examined in this study (Figure 5C–5E). This evidence concerns the gene MAPK3 and esophageal squamous cell carcinoma.