ADH1A and nephrocalcinosis: However, the presentation of hypocalcemia varies from mild asymptomatic to severe ones such as seizures, paraesthesias, carpopedal spasms or a febrile seizures, sometimes with severe outcome manifesting with tetany or laryngospasm.[5] Patients with ADH1 may also present with complications due to hypercalciuria, like renal stones, nephrocalcinosis, renal impairment and basal ganglia calcifications.[6] Interestingly considerable variation in the clinical presentation of 1 hypocalcemic family members can be observed.