TSHR and hyperthyroidism: In GD, relatively more T3 than T4 is produced and the ratio between FT4 and FT3 was shown to be significantly lower than in other types of hyperthyroidism.[13] Through stimulation of TSH-R, anti-TSH-R induced the expression of sodium iodide symporter, a key plasma membrane transport protein on the basolateral membrane of thyrocyte that enables active transport and thyroid uptake of iodide as well as radioactive iodine-123 or iodine-131.[3,14] Unfortunately, before admittance of the patient to our institution, a CT investigation with contrast media was performed during a diagnostic procedure.