Capsule endoscopy and/or balloon-assisted endoscopy have excellent capabilities in detecting lesions in the small intestine.[6,7] Meanwhile, calcification may be an external manifestation of some diseases, such as papillary thyroid carcinoma and necrotic adipose tissue and so on.[8,9] In addition, calcification occurred in gastric adenocarcinoma, and the cause is related to the parathyroid hormone secreted by adenocarcinoma.[10,11] However, up to now, there are few reports about calcification associated with GI bleeding. This evidence concerns the gene PTH and gastric adenocarcinoma.