VCP mutations are also linked to other degenerative diseases, including ALS, Parkinson's disease and muscular dystrophy (Kimonis et al., 2008b; Majounie et al., 2012; Abramzon et al., 2012; Mori et al., 2013; Liewluck et al., 2014; Kazamel et al., 2015; Al-Obeidi et al., 2018). Here, VCP is linked to amyotrophic lateral sclerosis.