HOXA13 and hand-foot-genital syndrome: HOXA5 and HOXA9 were overexpressed and hypomethylated in MRKH patients (Rall et al., 2011), and nonsense and missense HOXA13 mutations, as well as an expansion of the HOXA13 N-terminal polyalanine tract, have been reported as causative of HFGS (Mortlock and Innis, 1997; Goodman et al., 2000).