MVP and osteoporosis: Wheat germ agglutinin (WGA) staining and scanning electron microscopy (SEM) analysis revealed that the total resorption area of Mvpf/fLyz2-Cre osteoclasts was significantly higher than Mvpf/fosteoclasts (Figure 4J-M), corroborating our earlier studies that suggested MVP deletion in the monocyte cell lineage caused an osteoporosis-like phenotype by increasing osteoclastic bone resorption.