APOB and Marchiafava-Bignami disease: Results of the conditional logistic analyses showed an inverse association between serum levels of six metabolites and high-MBD BC cases, as well as for serum levels of the triglycerides lipid main fraction and 11 VLDL subfractions of triglycerides, cholesterol, phospholipids and APO B. One other metabolite was, on the other hand, directly associated with high-MBD BC cases.