TIMER database analysis showed that expression of TNFRSF14 was significantly downregulated in breast cancer, colon adenocarcinoma, lung squamous cell carcinoma, and EC tissues, and significantly upregulated in cholangiocarcinoma, kidney renal clear cell carcinoma, kidney renal papillary cell carcinoma, liver hepatocellular carcinoma, and prostate adenocarcinoma tissues compared to their corresponding normal tissues (Figure 10A). The gene discussed is TNFRSF14; the disease is cholangiocarcinoma.