Cytokines and chemokines, such as CCL18 [35], IL-6 [36], CXCL13 [37], IL-8 (CXCL8) [38], and CTACK, may be directly involved in the pathogenesis of fibrosis and are thus potential targets for IPF treatment. The gene discussed is CXCL8; the disease is idiopathic pulmonary fibrosis.