PED10A levels were found to be increased in MSNs and other subsets of striatal interneurons (ie, parvalbuminergic, somatostatinergic, and calretininergic interneurons) in R6/2 transgenic HD mice compared with the wild‐type mice, whereas striatal cholinergic interneurons PDE10A levels were lower.46 The gene discussed is PDE10A; the disease is Huntington disease.