ALDH7A1 and Parkinson disease: Moreover, UK‐343664 (ie, a PDE5 inhibitor) and MR1916 (ie, a PDE10A inhibitor) have also been reported to attenuate LID in 6‐OHDA rats86, 87 and parkinsonian monkeys,88 suggesting that PDE could, in fact, be targeted for preventing or treating LID in PD.