EIF2AK2 and hydrops fetalis: As shown in Figs. 5a (left panel),b,d,e, and g, the expression of PKR, as assessed by immunohistochemistry (Fig. 5a,b), western blotting (Fig. 5d,e), and qRT-PCR (Fig. 5g) was found significantly higher in the HF + STZ group when compared with the control group (p < 0.01) and at comparable levels with the control group in the HF + STZ + IHZ group.