When comparing HA, which is a biomarker of mesothelioma, and SMRP by focusing not on MPM but on BAPE, we found a significantly high AUC of 0.902 for SLPI and significantly lower AUCs for CYFRA21-1 (0.853), HA (0.802) and SMRP (0.746). This evidence concerns the gene MSLN and mesothelioma.